Biomedical Products Division:
MycoProSafe®
The most advanced ready to use kit for the fluidification, decontamination, and concentration of Tuberculosis
MycoProSafe® (MPS®) is a sample decontamination and concentration kit. It permits the processing of samples for microscopy, culture and molecular methods for identification and isolation of mycobacteria. It is intended for in vitro diagnostic use.
MPS is a kit that contains all the materials needed to safely perform the �sodium hydroxide - N-acetyl-L-cysteine decontamination and concentration method�. This method is recommended to increase efficiency in the recovery of mycobacteria from samples by selectively killing other microorganisms and liquefying samples like sputum for better sedimentation
Current Practices
Presently, materials needed for this purpose are either prepared by the laboratories that process the samples, or are purchased. In any case, the buffers used in this procedure are stored in big containers and they are a prime source of contamination, since they themselves are frequently contaminated during multiple uses.
Advantages of MycoProSafe
- MPS provides, in individual sets, all the materials needed for processing each sample.
- It eliminates the problem of cross-contamination while saving time and effort.
- Stable p.H. (6.8-7.0)
- It is designed to be disposed of safely, after processing biohazard material.
MPS uses the KUBICA technique (N-Acetyl-L-Cysteine, Sodium hydroxide concentrated to 2%, 3%, or 4%. It is also compatible with all techniques.
Principles of the procedure:
Clinical samples like sputum contain many microorganisms other than mycobacteria. Processing with sodium hydroxide -sodium citrate - N-acetyl-L-cysteine, decontaminates the samples by killing many microorganisms susceptible to sodium hydroxide while mycobacteria, that are resistant to alkaline pH, survive. N-acetyl-L-cysteine is a reducing substance that reduces the disulfide bonds of the mucus proteins which decreases viscosity of the sputum and thus liquefies the samples. This facilitates the sedimentation of bacilli during centrifugation.
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MycoProSafe Quick Application Guide
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